Theses and Dissertations

Issuing Body

Mississippi State University

Advisor

Brinkman, Eric

Committee Member

Mackin, Andrew

Committee Member

Linford, Robert

Committee Member

Archer, Todd

Date of Degree

5-17-2014

Document Type

Graduate Thesis - Open Access

Major

Veterinary Medical Science

Degree Name

Master of Science

College

College of Veterinary Medicine

Department

Veterinary Medical Science Program

Abstract

Hepatobiliary disease can sometimes be difficult to diagnosis due to non-specific clinical signs, and diagnostic imaging is a vital tool in diagnosing these diseases. Multi-slice computed tomographic cholangiography (MSCTC) is a non-invasive way to obtain high quality images of the hepatobiliary system. Our objectives were to determine the best technique for performing MSCTC in normal dogs with regards to contrast agent, dose, and optimal time to imaging. Our test subjects included eight normal adult hounds. Four dogs were administered Cholografin and the other four Biliscopin. Two dose groups were established with four dogs receiving 0.5mL/kg and four receiving 1 mL/kg. Our results demonstrated that MSCTC is feasible in normal dogs and produces high quality images of the hepatobiliary system. The contrast agent Biliscopin at the higher dose subjectively produced the best quality images. The optimal time to image patients following contrast administration varied between contrast agents (15-60 minutes).

URI

https://hdl.handle.net/11668/18104

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