Theses and Dissertations

Naresh Regmi

Issuing Body

Mississippi State University

Advisor

Liao, Shengfa

Committee Member

Crenshaw, Mark

Committee Member

Rude, Brian J.

Date of Degree

8-14-2015

Document Type

Graduate Thesis - Open Access

Major

Animal Science

Degree Name

Master of Science (M.S.)

College

College of Agriculture and Life Sciences

Department

Department of Animal and Dairy Sciences

Abstract

The objective of this study was to evaluate the effects of dietary lysine on plasma concentrations of amino acid (AAs) and other metabolites of finishing pigs. Eighteen crossbred late-stage finishing pigs (9 barrows and 9 gilts) were assigned to three dietary treatments, Diets I (lysine-deficient), II (lysineequate), and III (lysine-excess), according to a randomized complete block design with gender as block. After 4 weeks on trial, jugular vein blood were collected and centrifuged for plasma samples, which were analyzed for concentrations of 24 AAs using HPLC method and 6 selected metabolites related to major nutrient metabolism using ACE Alera Clinical Chemistry System. Dietary lysine had a significant effect on plasma concentrations of 13 AAs and 3 metabolites (albumin, cholesterol, and urea nitrogen). The patterns of AA and metabolite concentrations alteration indicated complex metabolic interactions between lysine and other AAs, which subsequently had effects on other metabolites and animal growth performance.

URI

https://hdl.handle.net/11668/20053

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