Lemley, Caleb O.
Hopper, Richard M.
Date of Degree
Graduate Thesis - Open Access
Progesterone is essential for the maintenance of pregnancy in cattle. Recent trends in decreased reproductive efficiency in dairy cattle have led researchers to believe that increased catabolism and decreased peripheral concentrations of progesterone are at fault. The objective of this study was to determine if the induction of an accessory corpus luteum (CL), via human chorionic gonadotropin (hCG), alters blood perfusion of CL, peripheral concentrations of progesterone, or hepatic steroid inactivating enzymes. We hypothesized that the induction of an accessory CL would decrease blood perfusion of the CL, decrease peripheral concentrations of progesterone, and increase clearance of progesterone in the liver. Total blood perfusion of the CL was increased in cows with 2 CL compared to cows with 1 CL, but concentrations of progesterone and hepatic enzymes did not differ. Overall, the increased blood perfusion in cows with 2 CL did not alter concentrations of progesterone or progesterone clearance.
Voelz, Benjamin Eugene, "Effect of Double Ovulation on Peripheral Concentrations of Progesterone, Luteal Blood Perfusion and Hepatic Steroid Inactivating Enzymes" (2014). Theses and Dissertations MSU. 1654.