Theses and Dissertations

Issuing Body

Mississippi State University


Wax, Benjamin, Jr.

Committee Member

Vickers, John Bradley

Committee Member

Gilliland, Katherine J.

Committee Member

Kavazis, Andreas N.

Date of Degree


Document Type

Graduate Thesis - Open Access


Exercise Physiology

Degree Name

Master of Science (M.S.)


College of Education


Department of Kinesiology


Ergogenic L-citrulline and malate are amino acids used in specific combination to effect muscular endurance during athletic performances. Purpose: The study aimed to investigate the ergogenic properties of citrulline-malate (CM) during a resistance training protocol. Methods: Utilizing a randomized, counterbalanced, double blind study, fifteen trained males completed a resistance training protocol once using placebo (PL) and once with CM (8.0g). Results: CM supplementation increased repetitions in chin-ups, reverse chin-ups, push-ups, and total trial repetitions. Blood lactate was significantly increased post-exercise compared to pre-exercise, but was not significantly different between CM and placebo. Further, a significant interaction effect was revealed for systolic blood pressure, a significant condition effect for diastolic blood pressure, and a significant time effect for HR. Post-hoc analysis revealed that SBP responses were more elevated in the placebo condition during recovery. Conclusion: Collectively, these novel findings suggest CM increases muscular endurance during upper body resistance exercise.