Theses and Dissertations

Issuing Body

Mississippi State University


Sharma, Chander Shekhar

Committee Member

Kiess, Aaron S.

Committee Member

Nannapaneni, Ramakrishna

Date of Degree


Document Type

Graduate Thesis - Open Access


Poultry Science

Degree Name

Master of Science (M.S.)


College of Agriculture and Life Sciences


Department of Poultry Science


Antimicrobial efficacy of recently approved lytic bacteriophage preparation Salmofresh™ against Salmonella was evaluated on chicken breast fillets as dip and surface application, which reduced Salmonella by 0.7-0.9 log CFU/g and 0.8-1 log CFU/g, respectively. Surface application of Salmofresh™ on Salmonella inoculated chicken breast followed by storage under modified atmosphere packaging (95% CO2/ 5% O2) reduced Salmonella by 1.2 log CFU/g. The combined application of Salmofresh™ with cetylpyridinium chloride (CPC) and lauric arginate (LAE) reduced Salmonella on chicken breast fillets by 1.2-1.4 log CFU/g and 0.9-1 log CFU/g, respectively. The sequential application of chemical antimicrobial (CPC, LAE, chlorine and peracetic acid) and Salmofresh™ in reducing Salmonella was tested in a chicken skin model. Dip treatment in peracetic acid (400ppm) followed by surface application of phage revealed the highest reduction of Salmonella up to 2.5 log CFU/cm2 on chicken skin.