Kiess, Aaron S.
Wamsley, Kelley G. S.
Date of Degree
Graduate Thesis - Open Access
College of Agriculture and Life Sciences
Department of Poultry Science
Lactic acid producing bacteria (LAB) and organic acids have been proposed as effective alternatives to antibiotics, however there is limited literature concerning their combination. Thus, the objective of this thesis was to investigate the effects of LAB, encapsulated butyric acid (EBA), and their combination. Under challenged conditions, the in vitro study demonstrated that both EBA and LAB were capable of reducing pathogen proliferation over time, with greater efficacy at lower initial concentration. However, EBA demonstrated a greater effectiveness on pathogen reduction. Under challenged conditions, the results of the in vivo study indicated that birds fed LAB performed comparatively to that of birds fed antibiotics concerning BW and FCR from d 0-45 and both diets enhanced gut physiology, pH and immune parameters. Overall, the results of the thesis indicate the ineffectiveness of combining EBA and LAB, while providing valuable evidence supporting LAB as an effective alternative to antibiotics.
Dittoe, Dana Kristen, "In Vitro and In Vivo Effects of an Encapsulated Butyric Acid and a Lactic Acid Producing Bacteria Used Alone or in Combination" (2017). Theses and Dissertations MSU. 2669.