Mississippi State University
Wise, David J.
Griffin, Matthew J.
Rosser, Thomas G.
Date of Degree
Graduate Thesis - Open Access
Master of Science
College of Forest Resources
Department of Wildlife, Fisheries and Aquaculture
Incidence and prevalence of Edwardsiella piscicida has increased in Mississippi farm-raised catfish in recent years. Edwardsiella piscicida affects mostly market-sized catfish during the final stages of the production cycle resulting in significant economic losses. The objectives of this study were to determine the genetic variability of E. piscicida, assess virulence in channel and hybrid catfish, and evaluate the capacity of a live-attenuated E. ictaluri vaccine to protect channel and hybrid catfish against heterologous E. piscicida isolates. This work identified five discrete E. piscicida lineages, along with group specific associations of several virulence related genes. In general, E. piscicida was shown more virulent in hybrids than channel catfish, in line with previous work. Further, a live-attenuated E. ictaluri vaccine was shown to confer cross-protective immunity in channel and hybrid catfish against E. piscicida.
US Department of Agriculture (USDA) Agricultural Research Service (Grant/Award Number: 58‐6402‐2729) USDA Catfish Health Research Initiative (Grant/Award Number: 6402‐31320‐002‐02)
Lopez Porras, Adrian, "Intraspecific Variability of Edwardsiella piscicida and Cross-Protective Efficacy of a Live-Attenuated Edwardsiella ictaluri Vaccine in Channel and Channel × Blue Hybrid Catfi" (2020). Theses and Dissertations. 2789.