Theses and Dissertations

Issuing Body

Mississippi State University


Williams, N. Lakiesha

Committee Member

Cooley, Jim

Committee Member

Liao, Jun

Committee Member

Horstemeyer, F. Mark

Date of Degree


Document Type

Graduate Thesis - Open Access


Biomedical Engineering

Degree Name

Master of Science


James Worth Bagley College of Engineering


Department of Agricultural and Biological Engineering


Due to traumatic brain injury (TBI), numerous studies have focused on comprehensively determining the mechanical properties of the brain. This study examined the strain rate dependence of porcine brain under compression, and the microstructural damage was quantified using a confocal microscope and graphical user interface (GUI). The selected strain rates were 0.10 s-1, 0.025 s-1, and 0.00625 s-1 while the strain levels targeted for confocal imaging were 15%, 30%, and 40%. This study also characterized the stress-state dependence at a strain rate and strain level of 0.10 s-1 and 40%, respectively, under compression, tension, and shear. Strain rate dependency data exhibited viscoelastic behavior, and the analysis parameters correlated with increasing strain rate and strain level. Stress-state dependency data demonstrated distinct nonlinear behavior, and disparities were observed in the analysis parameters between different testing modes. Finite element procedures can implement this supplementary data for devising more realistic models.



strain rate dependence||stress-state dependence||viscoelastic||traumatic brain injury