Theses and Dissertations

Issuing Body

Mississippi State University


Hollis, T. Keith

Committee Member

Rowland, Gerald

Committee Member

Emerson, Joseph P.

Date of Degree


Document Type

Graduate Thesis - Open Access

Degree Name

Master of Science


College of Arts and Sciences


Department of Chemistry


Methodologies for expanding the architectural diversity of -N-heterocyclic carbene (NHC) pincer ligand precursors and transition metal complexes have been developed for the production of more efficient catalyst, which will be employed in the synthesis of pharmaceuticals. An efficient route for the synthesis and isolation of bis-1,3-(3'-aryl-N-heterocycl-1'-yl)arenes has been established, and preliminary data for metalation and transmetalation of a N, N'-diaryl imidazolium salt has been acquired. Additionally, a proficient methodology for the synthesis of mixed, unsymmetrical -NHC pincer ligand precursors has been discovered, and preliminary data for mixed, unsymmetrical transition metal complexes is also included. These methodological expansions will lead to more efficient catalyst that decrease the expenditure of energy required for the synthesis of pharmaceuticals, thus making their synthesis more favorable for the environment and their price more affordable for consumers.



N-heterocyclic carbenes||unsymmetrical imidazolium salts||N-heterocyclic aryl salts||Pincer Ligands