Microwave Mild Hyperthermia Applicators for Chemo-Thermotherapy of Liver
Donohoe, J. Patrick
Ball, John E.
Younan, Nicolas H.
Date of Degree
Original embargo terms
MSU Only Indefinitely
Dissertation - Open Access
Electrical and Computer Engineering
Doctor of Philosophy
James Worth Bagley College of Engineering
Department of Electrical and Computer Engineering
Increasing demands for hyperthermia (HT) as an adjuvant therapy is caused from the contributions of thermal therapy to the traditional treatments. Latest improvements in hyperthermia make it popular among thermal therapies to cure cancer in any organ or body parts. HT takes advantage of EM radiation inside the tumor that provides temperature and blood perfusion increment that helps radiation therapy and chemotherapy to be more efficient. Therefore, some advantages makes HT preferred when compared to similar treatments. Being noninvasive and painless with an efficient cooling system, and helping to shorten the application period and session number of conventional treatments are most important advantages of HT. However, existing HT systems require high input power per elements on the applicators and long application time. Designing conformal and patient specific applicators with mild application can solve this issue. Moreover, mild HT application can make cancer treatment cheaper and more accessible. The main goal in this study is to design conformal HT applicators through optimization for liver and provide a patient specific and cost-effective local hyperthermia treatment that can be widely used in local clinical cancer treatment centers without expensive applicators.
Asili, Mustafa, "Microwave Mild Hyperthermia Applicators for Chemo-Thermotherapy of Liver" (2016). Theses and Dissertations MSU. 3103.