Mississippi State University
Ryan, Peter L.
Feugang, Jean M.N.
Filipov, Nickolay M.
Willard, Scott T.
Date of Degree
Dissertation - Open Access
Agricultural Life Sciences (Animal Physiology)
Doctor of Philosophy
College of Agriculture and Life Sciences
Department of Animal and Dairy Sciences
Angiogenesis is a central process to both physiological and pathological aspects of living organisms. Understanding the angiogenic system via the key mediator, vascular endothelial growth factor (VEGF), has led to the development of biophotonic models capable of monitoring how this process is programmed. The whole animal model tested here is based on the involvement of angiogenesis in a wound healing environment. This model proved to be functional as a system monitor but lacked the precision to yield significant results between the biological compounds tested (estrogen, methoxychlor, and relaxin). The in vitro model is based on angiogenesis in a cancer environment. This model proved to be both a valid and functional way of monitoring the biological compounds tested (CoCl2, epinephrine, and norepinephrine).
Youngblood, Ramey C, "Use of Biophotonic Models to Monitor Biological Compounds via the Angiogenic System" (2013). Theses and Dissertations MSU. 4862.