Theses and Dissertations

Issuing Body

Mississippi State University


Clay Cavinder

Committee Member

Thu T. Dinh

Committee Member

Caleb O. Lemley

Date of Degree


Original embargo terms


Document Type

Graduate Thesis - Open Access


Agricultural Science

Degree Name

Master of Science


College of Agriculture and Life Sciences


Department of Animal and Dairy Sciences


Equine athletes are subjected to environmental and physical stressors resulting in oxidative stress that can negatively impact performance. Oxidative stress can result in lipid peroxidation, cell damage, and DNA degradation leading to physiological dysfunction and increased instance of disease. It has been established that humans are able to adapt to oxidative stress when exposed to extended periods of high-intensity exercise, however, this has yet to be established in the equine model. In the present study, we sought to establish patterns of oxidative stress expression immediately following exercise and adaption to prolonged exposure to exercise training in the equine model. Results indicate horses express changes in oxidative stress biomarkers at the onset of exercise training but adapt with prolonged exercise regimes. Future research should focus on mitigation techniques and therapeutics for oxidative stress in equine athletes.