Theses and Dissertations


Issuing Body

Mississippi State University


Fountain, Brent J.

Committee Member

Cheng, Wen-Hsing

Committee Member

Smith, JohnEric

Committee Member

Conrad, Amanda

Committee Member

Schilling, Wes

Date of Degree


Document Type

Graduate Thesis - Open Access



Degree Name

Master of Science (M.S.)


College of Agriculture and Life Sciences


Department of Food Science, Nutrition and Health Promotion


This study investigated the effect of vitamin B-12 supplementation on visual response time (VRT). Menstrual cycle phase (MCP) and 24-hour dietary intake of B-12 were also observed as dependent variables. This blind, placebo-controlled trial observed 14 young adult females in four treatment groups: control, 500mcg (low dose), 2000mcg (moderate dose), and 3000mcg (high dose). The study lasted 28 days, with participants treated weekly, randomly assigned to each of the treatment groups. When comparing B-12 dose treatment groups to VRT baseline, there was significant improvements in VRT. Compared to the placebo, there were no significant differences among treatment groups. Significant differences were observed among MCP in two of the four treatment groups. No significant differences were observed in 24-hour intake of B-12 prior to treatment.