Theses and Dissertations

Issuing Body

Mississippi State University


Smith, David R.

Committee Member

Woodruff, Kimberly A.

Committee Member

Brookshire, Wilson C.

Date of Degree


Original embargo terms

Campus Access Only 1 Year

Document Type

Graduate Thesis - Campus Access Only


Veterinary & Biomedical Science

Degree Name

Master of Science (M.S.)


College of Veterinary Medicine


Department of Pathobiology and Population Medicine


Shelters often make euthanasia or adoption decisions based on the results of FeLV-FIV point-of-care tests but given the low estimated prevalence of these diseases and imperfect test performance, this might not be a good practice because of diagnostic error. The objectives of this study were to determine the true prevalence of FeLV and FIV in apparently healthy and sick shelter cats in Mississippi, estimate predictive value of the Zoetis Witness FeLV-FIV Rapid ImmunoMigration test results at the estimated true prevalences through Bayesian latent class modeling, and formulate testing recommendations for shelters. One chapter will review the literature on FeLV and FIV. The bulk of this thesis will focus on determining the true prevalence of retroviral infection in Mississippi shelter cat populations. The last chapter will use Bayesian modeling to estimate test performance and predictive value of test results in healthy and sick shelter cat populations.