Analytical Method For Detecting Pcb Derivatives At Low Levels In Surface Water Samples By Solid Phase Extraction-Liquid Chromatography/Mass Spectrometry

Author

Shannon Recca Alford

Issuing Body

Mississippi State University

Advisor

Alley, Earl

Committee Member

Armbrust, Kevin

Committee Member

Foster, Stephen

Date of Degree

5-7-2005

Document Type

Graduate Thesis - Open Access

Major

Chemistry

Degree Name

Master of Science

College

College of Arts and Sciences

Department

Department of Chemistry

Abstract

Polychlorinated biphenyls (PCBs) and their metabolic derivatives are ubiquitous environmental contaminants. These compounds are of concern because of their persistence and bioaccumulation in nature. PCBs and the hydroxylated metabolites have shown endocrine-disrupting activity. A method of detection in surface water samples is important to identify and quantify the environmental contamination. In this research we have attempted to develop a method of detection. Six representative polychloromethoxybiphenyls (PCMBs) were prepared. The corresponding polychlorobiphenylols, hydroxylated PCB metabolites (OH-PCBs), were prepared from the PCMBs. A method coupling solid phase extraction with liquid chromatography, on-line electrospray ionization, and mass spectrometry (SPE-LC/ESI/MS) was developed for detection of the OH-PCBs in distilled and surface water samples.

URI

https://hdl.handle.net/11668/17366

Recommended Citation

Alford, Shannon Recca, "Analytical Method For Detecting Pcb Derivatives At Low Levels In Surface Water Samples By Solid Phase Extraction-Liquid Chromatography/Mass Spectrometry" (2005). Theses and Dissertations. 670.
https://scholarsjunction.msstate.edu/td/670