"The in vitro effects of glucosamine on equine and canine platelet aggr" by Gabrielle Rands
 

Honors Theses

College

College of Veterinary Medicine

Department

College of Agriculture and Life Sciences

Degree

Bachelor of Science (B.S.)

Major

Biological Sciences

Abstract

Citrated blood samples were collected via jugular venipuncture and used to create platelet-rich plasma (PRP). PRP samples were incubated for 5 minutes with four concentrations of glucosamine: 0 µ/ml (control), 10 µ/ml, and 100 µ/ml. Platelet aggregation was determined using turbidometric aggregometry using ADP or collagen as agonists. Thromboxane B2 concentrations were measured using a commercially available ELISA kit. The results were analyzed using mixed model analysis. Significance was set at p<0.05.

Date Defended

5-1-2017

Thesis Director

Fontenot, Robin

Second Committee Member

Thomason, John

Third Committee Member

Clevinger, Donna

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