Theses and Dissertations
Issuing Body
Mississippi State University
Advisor
Donaldson, Janet R.
Committee Member
Carroll, Jeffery A.
Committee Member
Stewart, James A., Jr.
Committee Member
Thornton, Justin A.
Date of Degree
12-13-2014
Document Type
Graduate Thesis - Open Access
Major
Microbiology
Degree Name
Master of Science
College
College of Arts and Sciences
Department
Department of Biological Sciences
Abstract
The environment of the gastrointestinal (GI) tract is an extremely complex system made up of not only host cells, but also many beneficial microbes. Disruption of this environment can often lead to disorders and health issues. To help balance this system, probiotics have often been administered to both humans and animals, such as livestock. This study aimed to determine what beneficial effects a novel strain of Enterobacter cloacae, strain JD6301, could offer to a host in the presence of an enteric infection with E. coli O157:H7. Upon administration of JD6301, supplemented animals had overall less E. coli present in the colon and caecum. Moreover, these animals shed more E. coli than control groups. Supplemented animals also had increased concentrations of serum triglycerides one day prior to challenge. Together, these data suggest that Enterobacter cloacae JD6301 could perform as a novel probiotic providing energy and protection to the host.
URI
https://hdl.handle.net/11668/19033
Recommended Citation
Wilson, Jessica Grissett, "Investigation of the Beneficial Effect of Enterobacter Cloacae Strain JD6301 on Mice Challenged with Escherichia Coli O157:H7" (2014). Theses and Dissertations. 2854.
https://scholarsjunction.msstate.edu/td/2854
Comments
Escherichia coli||probiotic||Enterobacter cloacae