Theses and Dissertations
Issuing Body
Mississippi State University
Advisor
Wan, Xiufeng (Henry)
Committee Member
Pharr, G. Todd
Committee Member
Hanson, Larry
Committee Member
Hoblet, Kent H.
Date of Degree
8-9-2019
Original embargo terms
Worldwide
Document Type
Graduate Thesis - Open Access
Major
Veterinary Medical Science
Degree Name
Master of Science
College
College of Veterinary Medicine
Department
Department of Basic Sciences
Abstract
Sialic acids (Sias) are receptors for influenza A viruses (IAVs). The influence of individual sialyltransferases on the Sias expressed is not understood. Also, sensitive methods to distinguish Sias on the cells are lacking. Our goals were to establish a method to detect Sias on the cell and to evaluate the importance of CMP-sialic acid transporter (SLC35A1) and ST6 beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1) for IAV infection. Aproximity ligation assay was established to detect and quantify Sias.
URI
https://hdl.handle.net/11668/14591
Recommended Citation
Jiang, Kaijun, "Novel methods for detecting glycan receptors for influenza A virus and exploration of the function of the sialyltransferases on influenza viral infection" (2019). Theses and Dissertations. 3315.
https://scholarsjunction.msstate.edu/td/3315
Comments
Influenza virus||silica acid receptor||CRISPR||PLA