![Theses and Dissertations](../../assets/md5images/007ba8c2f9f7b20b26ed4b229bc29542.jpg)
Theses and Dissertations
Issuing Body
Mississippi State University
Advisor
Walters, Keisha B.
Committee Member
Elmore, Bill B.
Committee Member
Hill, Priscilla J.
Date of Degree
5-12-2012
Document Type
Graduate Thesis - Open Access
Major
Chemical Engineering
Degree Name
Master of Science
College
James Worth Bagley College of Engineering
Department
Dave C. Swalm School of Chemical Engineering
Abstract
Interactions of Asthma Drugs with Artificial Saliva and Mucus. Modeling pulmonary particulate transport requires related biofluid physicochemical properties. Aims included measuring the effects of common aerosol drugs on artificial saliva and diffusivities of asthma medications in mucus. Artificial saliva solutions doped with asthma medications were characterized by pH, interfacial tension, and rheology. To measure diffusion, drug concentration was monitored by time-dependent FTIR spectra, and diffusivity obtained using Fick¡¦s second law. Measured theophylline and albuterol diffusivities were ca. 10-6 cm2/s. Surface Modification of Polymer Films with Light-Emitting Chemicals. To develop a polymer film system that changed color in response to radiation, acid groups of poly(ethylene-co-acrylic acid) were used to attach two light-emitting polymers: 4„S-(octyloxy)-4-biphenylcarboxylic acid and 2,7-bis(bromomethyl)-9,9-dihexyl-9Hluorene. Each reaction step was confirmed using static contact angle goniometry, FTIR spectroscopy, and X-ray photoelectron spectroscopy. UV-Vis and fluorescence spectroscopy measured the absorption spectra. Modified films were irradiated (ƒÜ=254 nm) and produced blue emissions.
URI
https://hdl.handle.net/11668/18310
Recommended Citation
Cornell, Ashley Lynn, "Studies in Applied Materials Science: Drug-Biofluid Interactions and Light-Emitting Polymer Films" (2012). Theses and Dissertations. 4118.
https://scholarsjunction.msstate.edu/td/4118
Comments
film||light emission||polymer||saliva||albuterol||theophylline||mucus||diffusion||diffusion coefficient||polyethylene||radiation