Theses and Dissertations
Issuing Body
Mississippi State University
Advisor
Bumgardner, Joel D.
Committee Member
Puckett, Aaron
Committee Member
Ryan, Jack
Committee Member
Cooper, Robert
Committee Member
Elder, Steve
Date of Degree
12-11-2004
Document Type
Graduate Thesis - Open Access
Major
Biomedical Engineering
Degree Name
Master of Science
College
James Worth Bagley College of Engineering
Department
Department of Agricultural and Biological Engineering
Abstract
The material characteristics play a role in the suitability of chitosan for biomedical applications. This is not surprising since the degree of deacetylation of chitosan influences antimicrobial activity, degradation rate, immune reaction and mechanical properties such as strength and elongation. This study examines chitosans of variable material characteristics for wound and bone healing applications. Chitosan films of 76, 78, 80, 87, 91, 92, and 95% degree of deacetylation were tested in vitro for cellular responses by fibroblast and bone cell lines. The in vitro responses were compared to the material characteristics of molecular weight, degree of deacetylation, swelling index, and ash content.
URI
https://hdl.handle.net/11668/17272
Recommended Citation
Hamilton, Virginia, "An In Vitro Evaluation Of Chitosan As A Biomaterial Focusing On The Effects Of The Degree Of Deacetylation" (2004). Theses and Dissertations. 562.
https://scholarsjunction.msstate.edu/td/562