Theses and Dissertations

Advisor

Zhang, Li

Committee Member

Ramachandran, Reshma

Committee Member

Abdelhamed, Hossam

Committee Member

Kiess, Aaron S.

Committee Member

Boltz, Timothy

Date of Degree

5-10-2024

Original embargo terms

Visible MSU only 1 year

Document Type

Graduate Thesis - Campus Access Only

Major

Agriculture (Poultry Science)

Degree Name

Master of Science (M.S.)

College

College of Agriculture and Life Sciences

Department

Department of Poultry Science

Abstract

Salmonellosis, a significant foodborne illness in humans, is caused by Salmonella, with poultry and poultry products acting as significant reservoirs and sources of human infection. Salmonella enterica subspecies enterica serotype Reading has recently emerged as a notable foodborne pathogen responsible for extensive multistate human outbreaks in North America. This study focused on evaluating the capacity of the emerged serotype to colonize broiler breeder reproductive tissues and potentially contaminate eggs, indicating the potential for vertical transmission. For this investigation, two Salmonella Reading strains were utilized, one associated with outbreaks and another non-outbreak strain. Both strains were initially modified with bioluminescent marker genes to facilitate tracking post-experimental infection in broiler breeders. The results indicated that both strains could colonize the reproductive tract of infected hens and be transmitted vertically through the eggs. This finding enhances our understanding of the colonization and vertical transmission capabilities of this serotype in broiler breeders.

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