Theses and Dissertations

ORCID

https://orcid.org/0009-0003-1981-0062

Advisor

Seitz, Marc A.

Committee Member

Lee, Alison M.

Committee Member

Thomason , John M.

Date of Degree

5-10-2024

Original embargo terms

Immediate Worldwide Access

Document Type

Graduate Thesis - Open Access

Major

Veterinary and Biomedical Science (Veterinary Medical Research)

Degree Name

Master of Science (M.S.)

College

College of Veterinary Medicine

Department

Department of Clinical Sciences

Abstract

The use of brightness mode (B-mode) ultrasound (US), color Doppler (CD), and power Doppler (PD) can all help evaluate and characterize splenic lesions. A relatively new non-Doppler technology used to evaluate vasculature called B-Flow helps overcome certain limitations of CD and PD that affect visualization of blood flow. There are no studies describing the use of B-Flow characterizing splenic lesions in dogs. A total of 97 splenic lesions were evaluated. Splenic lesions that were larger than 2 cm, distorted the splenic capsule, or accompanied free fluid were significantly associated with malignancy. Lesions with tortuous internal vessels on CD or B-Flow were significantly associated with malignancy. Lesions with large internal vessels compared to external vessels on PD and B-Flow were significantly associated with malignancy. In conclusion, these B-mode and vascular characteristics on CD, PD and B-flow may help clinicians prioritize malignant etiologies over benign ones and prompt more aggressive diagnostic recommendations.

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