Calorie Restriction in Overweight Seniors: Response of Older Adults to a Dieting Study: The CROSSROADS Randomized Controlled Clinical Trial
ORCID
Buys: https://orcid.org/0000-0001-8547-056X
MSU Affiliation
College of Agriculture and Life Sciences; Department of Food Science, Nutrition and Health Promotion
Creation Date
2026-01-29
Abstract
We conducted a study designed to evaluate whether the benefits of intentional weight loss exceed the potential risks in a group of community-dwelling obese older adults who were at increased risk for cardiometabolic disease. The CROSSROADS trial used a prospective randomized controlled design to compare the effects of changes in diet composition alone or combined with weight loss with an exercise only control intervention on body composition and adipose tissue deposition (Specific Aim #1: To compare the effects of changes in diet composition alone or combined with weight loss with an exercise only control intervention on body composition, namely visceral adipose tissue), cardiometabolic disease risk (Specific Aim #2: To compare the effects of a change in diet composition alone or combined with weight loss with an exercise only control intervention on cardiometabolic disease risk), and functional status and quality of life (Specific Aim #3: To compare the effects of a change in diet composition alone or combined with weight loss with an exercise only control intervention on functional status and quality of life). Participants were randomly assigned to one of three groups: Exercise Only (Control) Intervention, Exercise + Diet Quality + Weight Maintenance Intervention, or Exercise + Diet Quality + Weight Loss Intervention. CROSSROADS utilized a lifestyle intervention approach consisting of exercise, dietary, and behavioral components. The development and implementation of the CROSSROADS protocol, including a description of the methodology, detailing specific elements of the lifestyle intervention, assurances of treatment fidelity, and participant retention; outcome measures and adverse event monitoring; as well as unique data management features of the trial results, are presented in this article.
Publication Date
11-25-2014
Publication Title
Journal of Nutrition in Gerontology and Geriatrics
Publisher
Taylor and Francis
First Page
376
Last Page
400
Recommended Citation
Haas, M. C., Bodner, E. V., Brown, C. J., Bryan, D., Buys, D. R., Keita, A. D., … Locher, J. L. (2014). Calorie Restriction in Overweight Seniors: Response of Older Adults to a Dieting Study: The CROSSROADS Randomized Controlled Clinical Trial. Journal of Nutrition in Gerontology and Geriatrics, 33(4), 376–400. https://doi.org/10.1080/21551197.2014.965993
